(jr) Research Associate Molecular Engineering/Antibody Production

Confo Therapeutics is the only GPCR company with a discovery engine that precisely targets desired GPCR conformations. This unique capability allows us to unlock a vast untapped potential for the discovery and development of breakthrough medicines. We are advancing a robust pipeline of large and small molecules focused on validated targets in endocrine and metabolic diseases, as well as addressing a broader array of critical unmet medical needs in collaboration with our partners. Our team of around 50 people is dedicated to advancing our technology, expanding our capabilities, and building out our pipeline in order to achieve the best possible therapeutic outcomes for patients.
 

Confo Therapeutics is located on the Technology Park in Ghent. More information about Confo’s technology and strategy can be found on www.confotherapeutics.com

For the expansion of our molecular engineering team we are currently looking for a
(jr) Research Associate Molecular Engineering.

The chosen candidate will be working in a collaborative team contributing to workflows for the production and characterization of antibody drug candidates.

The successful candidate will have the following responsibilities:

• Production of VHHs and VHH-Fc fusions in bacterial, yeast and mammalian host cells

• Purification and QC (a.o. SDS-PAGE, Western Blot) of VHHs and VHH-Fc fusions

• Design and ordering of plasmid constructs for expression of antibody fragments (VHH) and VHH-Fc fusions

• Assessment of biophysical stability of antibodies: DSF, aSEC, turbidity, DLS

• Careful documentation of experimental work, provide high-quality data on time and report results within electronic lab notebook

• Prepare and effectively present your experimental results (written and oral) to project teams

• Have strong interpersonal skills and interact effectively with your direct collaborators

• Help maintaining laboratory equipment and inventory levels for laboratory supply

Required expertise:

Our preferred candidate will have the following profile:

• Degree of Bachelor or Master in Life sciences or equivalent.

• Experience in a related field in biotech or pharma environment is a plus

• Experience with production and purification of VHHs and/or antibodies is a plus

• Experience in molecular biology, more specifically in cloning, DNA extraction and PCR, is an advantage

• Highly collaborative, self-motivated, team-oriented individual

• Ability to work in a fast-paced, highly integrated team environment where accuracy, accountability and timeliness are essential

Our offer:

• A competitive compensation package with extensive benefits;

• The chance to continuously grow as a professional, with exposure to all aspects of R&D in the company;

• A job where you can make the difference;

• An entrepreneurial and stimulating working environment in a growing and ambitious biotech company.